An In-depth Review Of Methandrostenolone Steroid

Methandrostenolone is a testosterone derivative that has strong anabolic and moderate androgenic properties. First synthesized in the 1960s, it quickly became a popular performance-enhancing steroid among professional athletes. Although it is listed as a Schedule III drug under the US Anabolic Steroid Act of 1990, it is still widely distributed in the US and used by athletes, especially bodybuilders.

An Overview

Methandrostenolone is a modified form of testosterone with a double bond of carbons between carbons 1 and 2, which temper its androgenic properties. This chemical structure also gives it a weaker binding affinity for androgen receptors compared to testosterone. Nevertheless, it has a lower affinity for serum-binding proteins and a longer half-life than testosterone. Its potency is due to its ability to interact with androgen receptors at the cellular level.

How It Works

Methandrostenolone binds and activates androgen receptors thereby enhancing protein synthesis, glycogenolysis (breakdown of glycogen to glycogen and glucose-6-phosphate), and muscle growth. Fortunately, the 17 α-methylation of this steroid enables it to pass through the liver largely unbroken, which can cause liver damage over time.


A study published by the National Institutes of Health (NIH) found that methandrostenolone enhances muscle growth, muscle size, strength, and overall athletic performance substantially. Participants in this study were observed over a period of six weeks meaning it produces results quickly.


The recommended dosage for men ranges from 25 to 50mg per day. However, the recommended dosage for women is slightly lower ranging from 10 to 20mg per day. The problem with methandrostenolone is it has strong masculinizing effects in women even when consumed in small doses. Take note you can stack this steroid with other performance-enhancing drugs including testosterone derivatives. However, read dosage instructions carefully and seek medical help immediately if you experience adverse effects. At this point, it is worth noting that food decreases the bioavailability of orally ingested methandrostenolone, meaning you should take it between meals for maximum effect.

The standard practice is to take methandrostenolone in cycles lasting between 6 to 8 weeks followed by a similar off/break period. It is not advisable to take methandrostenolone if you have been diagnosed with high blood pressure, cardiovascular disease, kidney damage, hypertension, breast cancer, liver damage, respiratory issues, or prostate cancer. It is also unwise for children as well as pregnant and breastfeeding women to take this steroid. In general, anyone with pre-existing health issues should consult a qualified medical practitioner before taking methandrostenolone.

Adverse Effects

Firstly, a study published in the journal Clinical Science found that methandrostenolone can cause non-muscle weight gain meaning users are prone to gaining excess weight. Other adverse effects include male pattern baldness, enlarged breast tissue, oily skin, gynecomastia, acne, elevated blood pressure, increased irritability, clitoral hypertrophy, insomnia, and increased aggression. The rule of thumb is to stop taking this steroid if you experience multiple adverse effects. Firnd more information about methandrostenolone here.

Where To Buy Methandrostenolone

Although methandrostenolone is available on many websites, make your purchases from sites that link to popular bodybuilding/weightlifting forums because they are likely to have earned the trust of seasoned athletes. In addition, evaluate shipping policies carefully because some retailers offer free shipping while others do not. You can also save a substantial amount of money by purchasing this steroid from sites that offer discounts and promotions such as buy two bottles get one free.

Injectable versus Oral Administration

Methandrostenolone is available in various forms including tablets, injections, or capsules. If you intend to take methandrostenolone during meals, the injectable form is the right choice to avoid compromising its bioavailability. Nevertheless, the Centers for Disease Control and Prevention (CDC) says injecting substances into your body increases the risk of gravitating towards drug abuse. Using needles also increases the risk of contracting diseases like HIV especially for people sharing injections with others.


Methandrostenolone is a potent testosterone-family steroid that is used to enhance athletic performance and bulk up. In the US, it is categorized as a Schedule III Anabolic Steroid meaning its distribution and sale is subject to regulatory oversight. This notwithstanding, methandrostenolone for sale is available on sites that promote dietary supplements and bodybuilding products.

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